Protein Modification Reagents
New England Biolabs, Inc. Endo D – 1500 units
Endo D is a recombinant glycosidase, which cleaves within the chitobiose core of paucimannose N-linked glycans, with or without extensions in the antennae. Endo D is tagged with a chitin binding domain (CBD) for easy removal from a reaction, and is supplied glycerol-free for optimal performance in HPLC and MS- intensive methods.
Medchemexpress LLC 5,8-dioxa-2,11-diazatetradecanoic acid 14-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl) methyl ester | 2675364-08-4 | 98.1% | 475.53 | C24H33N3O7 | 10 MG
BCN-endo-PEG2-maleimide is an ADC linker that combines an endo-bicyclononyne (BCN) reactive group, a PEG2 spacer, and a maleimide thiol-reactive moiety for use in click chemistry and thiol conjugation workflows.
- High purity suitable for conjugation (98.1%).
- Provides a BCN moiety for strain-promoted azide-alkyne cycloaddition.
- Maleimide group enables selective thiol coupling.
- PEG2 spacer improves aqueous solubility and reduces steric hindrance.
- Molecular weight 475.53 g/mol; formula C24H33N3O7.
- Available in small research quantities (for example, 10 mg).
eMolecules Broadpharm Fmoc-N-amido-PEG4-acid 250mg 200183427 BP-20989 98 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
Broadpharm Fmoc-N-amido-PEG4-acid 250mg 200183427 BP-20989 98 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
Medchemexpress LLC Bis-Mal-Lysine-PEG4-TFP ester | 1426164-53-5 | 98.0% | C37H45F4N5O13 | 25 MG
Bis-Mal-Lysine-PEG4-TFP ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules connect a ligand for an E3 ubiquitin ligase with a ligand for a target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system. It is intended for research use only. For optimal stability, store at 4°C, protected from light. When in solvent, store at -80°C for 6 months or -20°C for 1 month, also protected from light.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system for selective protein degradation
- Highly soluble in DMSO (100 mg/mL)
- Demonstrates good solubility in various in vivo protocols
Creative Biomart Pancrelipase
The product, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.
Avanti Polar Lipids 18:0 PEG2000 PE Chloroform | 474922-77-5 | 200mg
18:0 PEG2000 PE Chloroform | Purity: 99% | 474922-77-5 | 200mg
Medchemexpress LLC 4-Arm PEG-SCM MW 20 100mg
4-Arm PEG-SCM (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery[1]
Worthington Biochemical Corporation COLLAGENASE (ANIMAL ORI 1GM
Prepared cultures grown in medium completely devoid of animal based components and designed for bioprocessing applications where introduction of animal derived pathogens must be prevented. 2593-92-3
Worthington Biochemical Corporation STEMXYME 2 COLLAGENASE 50MG
A specialized combination of Animal Origin-Free Clostridium histolyticum collagenase (Code: CLSAFB) and animal origin free Bacillus polymyxa neutral protease with a minimum of 250 CLS units and 2,000 caseinase units per mg dry weight. Designed for stem cell and other primary cell isolations and bioprocessing applications where introduction of potential animal derived pathogens must be prevented. 2593-92-3
Medchemexpress LLC DBCO-mPEG (MW 5kDa) | 99.1% | 100 MG
DBCO-mPEG (MW 5kDa) is a PEG-based PROTAC linker that plays a crucial role in the synthesis of PROTACs. This compound acts as a click chemistry reagent, incorporating a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs themselves are engineered with two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein, allowing for the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains a DBCO group for SPAAC with azide-containing molecules
- Enables selective degradation of target proteins
Medchemexpress LLC 1,2,4,5-Tetrazine, 3-methyl-6-[4-(3,6,9,12-tetraoxapentadec-14-yn-1-yloxy)phenyl]- | 1802907-97-6 | 98.0% | C20H26N4O5 | 25 MG
Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules composed of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets a protein of interest. They function by exploiting the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
- Functions as a PEG-based PROTAC linker
- Used for the synthesis of PROTACs
- Enables selective degradation of target proteins
- Utilizes the intracellular ubiquitin-proteasome system
Broadpharm Iodoacetamido-PEG6-azide| 100mg| 1240737-77-2| Purity 98%
Iodoacetamido-PEG6-azide| 100mg| 1240737-77-2| Purity 98%